Wwp2^em2Asah
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wwp2^em2Asah
• Name: WW domain containing E3 ubiquitin protein ligase 2; endonuclease-mediated mutation 2, Hiroshi Asahara
• MGI ID: MGI:6359820
• Synonyms: Wwp2^1del
• Gene: Wwp2 Location: Chr8:108162997-108285227 bp, + strand Genetic Position: Chr8, 54.15 cM
• Alliance: Wwp2^em2Asah page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 2 resulted in the deletion of a single G nucleotide, resulting in a frameshift and premature termination. (J:278573)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wwp2 Mutation: 373 strains or lines available

Notes

Generated in conjunction with Mir140^em2Asah.

References

• Original: J:278573 Inui M, et al., Dissecting the roles of miR-140 and its host gene. Nat Cell Biol. 2018 May;20(5):516-518
• All: 1 reference(s)