Mir140^em1Asah
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir140^em1Asah
• Name: microRNA 140; endonuclease-mediated mutation 1, Hiroshi Asahara
• MGI ID: MGI:6359823
• Synonyms: miR-140^14del
• Gene: Mir140 Location: Chr8:108277876-108277945 bp, + strand Genetic Position: Chr8, 54.33 cM
• Alliance: Mir140^em1Asah page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeted of exon 2 resulted in a 14 nucleotide deletion and a frameshift premature termination. (J:278573)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir140 Mutation: 3 strains or lines available

References

• Original: J:278573 Inui M, et al., Dissecting the roles of miR-140 and its host gene. Nat Cell Biol. 2018 May;20(5):516-518
• All: 1 reference(s)