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Abtb2tm1Zgwg
Targeted Allele Detail
Summary
Symbol: Abtb2tm1Zgwg
Name: ankyrin repeat and BTB domain containing 2; targeted mutation 1, Zhugang Wang
MGI ID: MGI:6359867
Synonyms: BPOZ2-
Gene: Abtb2  Location: Chr2:103396655-103548768 bp, + strand  Genetic Position: Chr2, 54.43 cM
Alliance: Abtb2tm1Zgwg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:278621
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv x C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsAlmost the entire gene, from the 3' part of exon 1 through exon 12, was replaced with a neomycin resistance gene cassette using homologous recombination. (J:278621)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abtb2 Mutation:  47 strains or lines available
References
Original:  J:278621 Zhang F, et al., Deficiency of BPOZ2 Decreases Liver Fibrosis After Chronic Carbon Tetrachloride Administration in Mice. Int J Toxicol. 2015 Mar-Apr;34(2):204-10
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory