Cx3cl1^tm1.1Yono
Targeted Allele Detail

Summary

• Symbol: Cx3cl1^tm1.1Yono
• Name: C-X3-C motif chemokine ligand 1; targeted mutation 1.1, Yuichi Ono
• MGI ID: MGI:6360180
• Gene: Cx3cl1 Location: Chr8:95498808-95509055 bp, + strand Genetic Position: Chr8, 46.79 cM
• Alliance: Cx3cl1^tm1.1Yono page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271242
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was flanked by loxP sites and a neomycin-resistance gene cassette flanked by vCre recombinase target sites (vloxP) was inserted downstream of the floxed exon. Cre-mediated recombination removed exon 2. (J:271242)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cx3cl1 Mutation: 35 strains or lines available

Notes

ES cell line = B6J-S1UTR (C57BL/6J).

References

• Original: J:271242 Morita N, et al., GPR31-dependent dendrite protrusion of intestinal CX3CR1(+) cells by bacterial metabolites. Nature. 2019 Feb;566(7742):110-114
• All: 1 reference(s)