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Tg(Ace-Tiam2)C1L2Bgh
Transgene Detail
Summary
Symbol: Tg(Ace-Tiam2)C1L2Bgh
Name: transgene insertion C1L2, Bernhard G Herrmann
MGI ID: MGI:6360715
Synonyms: Tg2L
Transgene: Tg(Ace-Tiam2)C1L2Bgh  Location: unknown  
Alliance: Tg(Ace-Tiam2)C1L2Bgh page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe promoter including the transcriptional start site drives expression of the long transcript (with the rabbit beta-globin polyadenylation signal including an intron and the SV40 polyadenylation signal) during spermiogenesis. The expression cassette is flanked by two copies of the chicken beta-globin insulator. Line C1L2 was generated. (J:273736)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:273736 Charron Y, et al., Two isoforms of the RAC-specific guanine nucleotide exchange factor TIAM2 act oppositely on transmission ratio distortion by the mouse t-haplotype. PLoS Genet. 2019 Feb;15(2):e1007964
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory