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Pogztm1.2Jrk
Targeted Allele Detail
Summary
Symbol: Pogztm1.2Jrk
Name: pogo transposable element with ZNF domain; targeted mutation 1.1, Jonathan R Keller
MGI ID: MGI:6360952
Gene: Pogz  Location: Chr3:94744878-94789637 bp, + strand  Genetic Position: Chr3, 40.74 cM
Alliance: Pogztm1.2Jrk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:271614
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 13. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 19. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 13 through 19 floxed. (J:271614)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 23 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pogz Mutation:  54 strains or lines available
References
Original:  J:271614 Gudmundsdottir B, et al., POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory