Nus1tm1.2Qrm
Targeted Allele Detail
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Symbol: |
Nus1tm1.2Qrm |
Name: |
NUS1 dehydrodolichyl diphosphate synthase subunit; targeted mutation 1.2, Qing Robert Miao |
MGI ID: |
MGI:6361026 |
Synonyms: |
NgBRKO, Nus1ko |
Gene: |
Nus1 Location: Chr10:52293643-52316279 bp, + strand Genetic Position: Chr10, 26.64 cM
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Alliance: |
Nus1tm1.2Qrm page
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Germline Transmission: |
Earliest citation of germline transmission:
J:229464
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Parent Cell Line: |
E14TG2a (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 2 and a loxP site and FRT-flanked neo cassette were inserted downstream of exon 4 via homologous recombination. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination in the germline removed exons 2-4.
(J:229464)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nus1 Mutation: |
19 strains or lines available
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Original: |
J:229464 Rana U, et al., Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice. Dev Biol. 2016 Feb 15;410(2):190-201 |
All: |
1 reference(s) |
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