Trim17^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trim17^em1Osb
• Name: tripartite motif-containing 17; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6361133
• Gene: Trim17 Location: Chr11:58845511-58863923 bp, + strand Genetic Position: Chr11, 36.38 cM, cytoband B1.2-B1.3
• Alliance: Trim17^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting exon 2 in both variants and the 3' UTR region downstream the coding region of exon7 in variant 2 to produce a 6312 bp deletion. (J:279039)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Trim17 Mutation: 37 strains or lines available

References

• Original: J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
• All: 1 reference(s)