Prss44^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss44^em1Osb
• Name: serine protease 44; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6361142
• Gene: Prss44 Location: Chr9:110642987-110647067 bp, + strand Genetic Position: Chr9, 60.79 cM
• Alliance: Prss44^em1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279100
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted the first through last coding exon (3293 bp). (J:279100)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Prss44 Mutation: 19 strains or lines available

References

• Original: J:279100 Holcomb RJ, et al., The testis-specific serine proteases Prss44, Prss46, and Prss54 are dispensable for mouse fertility. Biol Reprod. 2019 Aug 12
• All: 1 reference(s)