Tktl2^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tktl2^em1Osb
• Name: transketolase-like 2; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6361155
• Gene: Tktl2 Location: Chr8:66964408-66970987 bp, + strand Genetic Position: Chr8, 33.14 cM, cytoband B3.3
• Alliance: Tktl2^em1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279039
• Parent Cell Line: EGR-G101 (ES Cell)
• Strain of Origin: C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 1748 bp. (J:279039)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tktl2 Mutation: 39 strains or lines available

References

• Original: J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
• All: 1 reference(s)