Hmgb4^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hmgb4^em1Osb
• Name: high-mobility group box 4; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6361167
• Gene: Hmgb4 Location: Chr4:128154005-128154688 bp, - strand Genetic Position: Chr4, 61.97 cM
• Alliance: Hmgb4^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 7 bp. (J:279039)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Hmgb4 Mutation: 9 strains or lines available

References

• Original: J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
• All: 1 reference(s)