Ly6a^{tm1(cre/ERT2)Bzsh}
Targeted Allele Detail

Summary

• Symbol: Ly6a^{tm1(cre/ERT2)Bzsh}
• Name: lymphocyte antigen 6 family member A; targeted mutation 1, Bin Zhou
• MGI ID: MGI:6361441
• Synonyms: Sca1-2A-CreER
• Gene: Ly6a Location: Chr15:74866726-74869880 bp, - strand Genetic Position: Chr15, 34.29 cM
• Alliance: Ly6a^{tm1(cre/ERT2)Bzsh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278876
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Ly6a^{tm1(cre/ERT2)Bzsh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ly6a (MGI:107527)

• Mutation details: A targeting vector containing a 2A self-cleaving peptide sequence and CreER was inserted after the last exon inframe with Ly6a coding region. (J:278876)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ly6a (mouse) Summary of all recombinase alleles driven by Ly6a. Comparative matrix view of recombinase activities Alliance mouse Ly6a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ly6a Mutation: 22 strains or lines available

References

• Original: J:278876 Tang J, et al., Fate Mapping of Sca1(+) Cardiac Progenitor Cells in the Adult Mouse Heart. Circulation. 2018 Dec 18;138(25):2967-2969
• All: 1 reference(s)