Bcl7a^tm1.1Ban
Targeted Allele Detail

Summary

• Symbol: Bcl7a^tm1.1Ban
• Name: B cell CLL/lymphoma 7A; targeted mutation 1.1, Daniele Bano
• MGI ID: MGI:6361907
• Synonyms: Bcl7a^KO
• Gene: Bcl7a Location: Chr5:123482511-123512146 bp, + strand Genetic Position: Chr5, 62.92 cM, cytoband F
• Alliance: Bcl7a^tm1.1Ban page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279171
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed exon 2 and the neo cassette. (J:279171)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl7a Mutation: 27 strains or lines available

References

• Original: J:279171 Wischhof L, et al., The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function. Sci Rep. 2017 Dec 6;7(1):17055
• All: 2 reference(s)