Noc4l^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Noc4l^tm1.1Nju
• Name: NOC4 like; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6362739
• Gene: Noc4l Location: Chr5:110796285-110801248 bp, - strand Genetic Position: Chr5, 53.69 cM
• Alliance: Noc4l^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:247476
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 3 and a FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 3. Cre-mediated recombination deleted exon 3 and the selection cassette. (J:247476)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Noc4l Mutation: 24 strains or lines available

References

• Original: J:247476 Qin Y, et al., Targeted disruption of Noc4l leads to preimplantation embryonic lethality in mice. Protein Cell. 2017 Mar;8(3):230-235
• All: 2 reference(s)