Zdhhc5^tm1.1Smoc
Targeted Allele Detail

Summary

• Symbol: Zdhhc5^tm1.1Smoc
• Name: zinc finger, DHHC domain containing 5; targeted mutation 1.1, Shanghai Model Organisms Center
• MGI ID: MGI:6363129
• Synonyms: Dhhc5^flox
• Gene: Zdhhc5 Location: Chr2:84518314-84545524 bp, - strand Genetic Position: Chr2, 49.45 cM
• Alliance: Zdhhc5^tm1.1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270120
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette and left exon 4 floxed. (J:270120)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdhhc5 Mutation: 32 strains or lines available

References

• Original: J:270120 Wang J, et al., DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep. 2019 Jan 2;26(1):209-221.e5
• All: 1 reference(s)