Zdhhc4^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zdhhc4^em1Smoc
• Name: zinc finger, DHHC domain containing 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6363130
• Gene: Zdhhc4 Location: Chr5:143302244-143315007 bp, - strand Genetic Position: Chr5, 82.08 cM, cytoband G2
• Alliance: Zdhhc4^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 4 removed 341 bp encompassing the exon. (J:270120)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zdhhc4 Mutation: 24 strains or lines available

References

• Original: J:270120 Wang J, et al., DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane. Cell Rep. 2019 Jan 2;26(1):209-221.e5
• All: 1 reference(s)