Usp11^tm1Tac
Targeted Allele Detail

Summary

• Symbol: Usp11^tm1Tac
• Name: ubiquitin specific peptidase 11; targeted mutation 1, Taconic
• MGI ID: MGI:6363163
• Gene: Usp11 Location: ChrX:20570148-20586778 bp, + strand Genetic Position: ChrX, 16.2 cM
• Alliance: Usp11^tm1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:270214
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 3 - 12 were replaced with a lacZ and neo cassette via homologous recombination. (J:270214)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp11 Mutation: 17 strains or lines available

References

• Original: J:270214 Park MK, et al., PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nat Commun. 2019 Feb 7;10(1):636
• All: 1 reference(s)