Gprin3^em1Sns
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gprin3^em1Sns
• Name: GPRIN family member 3; endonuclease-mediated mutation 1, Serge N Schiffmann
• MGI ID: MGI:6363182
• Gene: Gprin3 Location: Chr6:59324211-59403279 bp, - strand Genetic Position: Chr6, 28.48 cM
• Alliance: Gprin3^em1Sns page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR/Cas9 technology inserted 1 bp in codon 15 creating a frameshift and a premature STOP codon. (J:279507)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gprin3 Mutation: 31 strains or lines available

References

• Original: J:279507 Karadurmus D, et al., GPRIN3 Controls Neuronal Excitability, Morphology, and Striatal-Dependent Behaviors in the Indirect Pathway of the Striatum. J Neurosci. 2019 Sep 18;39(38):7513-7528
• All: 1 reference(s)