Tmprss11f^em3Bug
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmprss11f^em3Bug
• Name: transmembrane protease, serine 11f; endonuclease-mediated mutation 3, Thomas H Bugge
• MGI ID: MGI:6364133
• Gene: Tmprss11f Location: Chr5:86669757-86780283 bp, - strand Genetic Position: Chr5, 43.56 cM
• Alliance: Tmprss11f^em3Bug page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting deleted 3 bp and inserted 404 bp (c.122_124delTCGinsGAGCACATGGGCACATGAACAAAGTGGCCATGGTGGTCGAGATGGAGGTTATGCTTGGGCTCAGCAACATGGGCTTCCACTCACCAAGGCTGACCTGGCTACAGCTGCTGCTGATTGCCAGATCTGCCAACAGCAGAAACCAACACTGAGCCCCAGATATGGCACCATTCCTCGAGGTGACCAGCCAGCAACCTGGTGGCAGGTTGACTACATTGGACCACTTCCTTCGTGGAAAGGACAGCGTTTTGTTCTTACTGGAGTAGATACTTATTCTGGTTATGGATTTGCCTTTCCTGCACGTAATGCCTCTGCTAAAACCACCATTCACGGACTGACAGAATGCCTCATCTATCGTCATGGTATTCCACACAGTATTGCTTCTGACCAAGGAACTCATTTCACAT; I41fsX90). (J:279596)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmprss11f Mutation: 39 strains or lines available

References

• Original: J:279596 Callies LK, et al., Iterative, multiplexed CRISPR-mediated gene editing for functional analysis of complex protease gene clusters. J Biol Chem. 2019 Sep 9
• All: 1 reference(s)