Gata6os^em2Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gata6os^em2Zfa
• Name: GATA binding protein 6, opposite strand; endonuclease-mediated mutation 2, Zusen Fan
• MGI ID: MGI:6364853
• Synonyms: LncGata6^Stop
• Gene: Gata6os Location: Chr18:11042037-11052567 bp, - strand Genetic Position: Chr18, 5.62 cM
• Alliance: Gata6os^em2Zfa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting inserted SV40 poly(A) (STOP) into the promoter. (J:268724)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata6os Mutation: 0 strains or lines available

References

• Original: J:268724 Zhu P, et al., LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis. Nat Cell Biol. 2018 Oct;20(10):1134-1144
• All: 1 reference(s)