Ehf^em1Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ehf^em1Zfa
• Name: ets homologous factor; endonuclease-mediated mutation 1, Zusen Fan
• MGI ID: MGI:6364857
• Gene: Ehf Location: Chr2:103093776-103133620 bp, - strand Genetic Position: Chr2, 54.43 cM
• Alliance: Ehf^em1Zfa page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 2 removed 4 bp (GGAC). (J:268724)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ehf Mutation: 27 strains or lines available

References

• Original: J:268724 Zhu P, et al., LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis. Nat Cell Biol. 2018 Oct;20(10):1134-1144
• All: 1 reference(s)