Clec16a^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Clec16a^em1(IMPC)J
• Name: C-type lectin domain family 16, member A; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6367564
• Gene: Clec16a Location: Chr16:10363203-10562742 bp, + strand Genetic Position: Chr16, 5.68 cM
• Alliance: Clec16a^em1(IMPC)J page
• IMPC: Clec16a gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTTGAGTTGTGCTTGTTACT and GTGTCAAGCTAGTCCAAGCG, which resulted in a 274 bp deletion beginning at Chromosome 16 position 10,568,310 bp and ending after 10,568,583 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001011715 (exon 4) and 125 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 114 and early truncation 3 amino acids later. (J:188991)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Clec16a Mutation: 48 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)