Snx6^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Snx6^tm1.1Nju
• Name: sorting nexin 6; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:6368549
• Synonyms: Snx6^fl
• Gene: Snx6 Location: Chr12:54793124-54842464 bp, - strand Genetic Position: Chr12, 23.46 cM
• Alliance: Snx6^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240866
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette and left exon 5 floxed. (J:240866)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snx6 Mutation: 62 strains or lines available

References

• Original: J:240866 Niu Y, et al., Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory. Elife. 2017 Jan 30;6:e20991
• All: 1 reference(s)