Ormdl3^em1Quli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ormdl3^em1Quli
• Name: ORM1-like 3 (S. cerevisiae); endonuclease-mediated mutation 1, Qiji Liu
• MGI ID: MGI:6369059
• Synonyms: Ormdl3^-
• Gene: Ormdl3 Location: Chr11:98472120-98478071 bp, - strand Genetic Position: Chr11, 62.07 cM
• Alliance: Ormdl3^em1Quli page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• A TALEN mutagenesis was used to introduce a truncated mutation within the third exon of Ormdl3 gene. (J:251260)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ormdl3 Mutation: 10 strains or lines available

References

• Original: J:251260 Dang J, et al., ORMDL3 Facilitates the Survival of Splenic B Cells via an ATF6alpha-Endoplasmic Reticulum Stress-Beclin1 Autophagy Regulatory Pathway. J Immunol. 2017 Sep 1;199(5):1647-1659
• All: 2 reference(s)