Nudt7^em1Ejj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nudt7^em1Ejj
• Name: nudix hydrolase 7; endonuclease-mediated mutation 1, Eun-Jung Jin
• MGI ID: MGI:6369729
• Gene: Nudt7 Location: Chr8:114860314-114881471 bp, + strand Genetic Position: Chr8, 60.53 cM
• Alliance: Nudt7^em1Ejj page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• TALEN technology generated a null allele. (J:266261)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nudt7 Mutation: 15 strains or lines available

References

• Original: J:266261 Song J, et al., Dysregulation of the NUDT7-PGAM1 axis is responsible for chondrocyte death during osteoarthritis pathogenesis. Nat Commun. 2018 Aug 24;9(1):3427
• All: 2 reference(s)