Tmem45a^tm1.1Urfm
Targeted Allele Detail

Summary

• Symbol: Tmem45a^tm1.1Urfm
• Name: transmembrane protein 45a; targeted mutation 1.1, University of Namur
• MGI ID: MGI:6370168
• Synonyms: Tmem45a^{tm1b(KOMP)Mbp}
• Gene: Tmem45a Location: Chr16:56625524-56706529 bp, - strand Genetic Position: Chr16, 34.22 cM, cytoband C1.1
• Alliance: Tmem45a^tm1.1Urfm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235703
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Using the IMPC targeting vector PG00253_Z_5_A04, the reporter/selection cassette (FRT site, lacZ reporter gene, loxP site, neomycin resistance cassette, FRT site and loxP site) was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. Cre-mediated recombination removed the selection cassette and exons 3 and 4. (J:235703)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem45a Mutation: 31 strains or lines available

References

• Original: J:235703 Hayez A, et al., TMEM45A Is Dispensable for Epidermal Morphogenesis, Keratinization and Barrier Formation. PLoS One. 2016;11(1):e0147069
• All: 2 reference(s)