Mir139^em1Jwli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir139^em1Jwli
• Name: microRNA 139; endonuclease-mediated mutation 1, Jianwen Liu
• MGI ID: MGI:6370186
• Gene: Mir139 Location: Chr7:101124583-101124650 bp, + strand Genetic Position: Chr7, 54.59 cM
• Alliance: Mir139^em1Jwli page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting generated a knockout allele.

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Mir139^em1Jwli

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir139 Mutation: 0 strains or lines available

References

• Original: J:280467 Maoa R, et al., The loss of MiR-139-5p promotes colitis-associated tumorigenesis by mediating PI3K/AKT/Wnt signaling. Int J Biochem Cell Biol. 2015 Dec;69:153-61
• All: 2 reference(s)