Marveld1^tm1.1Liy
Targeted Allele Detail

Summary

• Symbol: Marveld1^tm1.1Liy
• Name: MARVEL (membrane-associating) domain containing 1; targeted mutation 1.1, Yu Li
• MGI ID: MGI:6377090
• Gene: Marveld1 Location: Chr19:42135879-42140137 bp, + strand Genetic Position: Chr19, 35.84 cM
• Alliance: Marveld1^tm1.1Liy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279065
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked pgk-neo cassette and loxP site were inserted downstream of exon 1 via homologous recombination. Flp mediated recombination removed the pgk-neo cassette. (J:279065, J:280829)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Marveld1 Mutation: 4 strains or lines available

References

• Original: J:279065 Liu W, et al., MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development. Cell Death Dis. 2018 Sep 24;9(10):999
• All: 2 reference(s)