Trim36^tm1Htan
Targeted Allele Detail

Summary

• Symbol: Trim36^tm1Htan
• Name: tripartite motif-containing 36; targeted mutation 1, Hiromitsu Tanaka
• MGI ID: MGI:6378209
• Gene: Trim36 Location: Chr18:46298367-46345674 bp, - strand Genetic Position: Chr18, 24.41 cM
• Alliance: Trim36^tm1Htan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:307617
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Using standard homologous recombination in ES cells, a neomycin resistance cassette was introduced into the Trim36 gene to replace the exon 2, produceing a null allele. (J:307617)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Trim36 Mutation: 47 strains or lines available

References

• Original: J:307617 Aoki Y, et al., Haprin-deficient spermatozoa are incapable of in vitro fertilization. Mol Reprod Dev. 2020 May;87(5):534-541
• All: 1 reference(s)