Tg(Drd2-flpo)3BBsab
Transgene Detail

Summary

• Symbol: Tg(Drd2-flpo)3BBsab
• Name: transgene insertion 3B, Bernardo Sabatini
• MGI ID: MGI:6378545
• Transgene: Tg(Drd2-flpo)3BBsab Location: unknown
• Alliance: Tg(Drd2-flpo)3BBsab page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Drd2-flpo)3BBsab expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Drd2 (MGI:94924)

• Mutation details: A transgene derived from a BAC clone bMQ313M14 containing the mouse Drd2 (dopamine receptor D2) promoter modified to no longer drive expression of dopamine 2 receptors and expresses codon-optimized Flp (flpo) recombinase. No other genes are reported to be expressed from the BAC. The transgenic vector was introduced to FVB embryos. A loxP-flanked neomycin selection cassette originally located just 3' of Flp has been excised. This is founder line 3B. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Drd2 (mouse) Summary of all recombinase alleles driven by Drd2. Alliance mouse Drd2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)