Tg(Krt13-cre)139Gaff
Transgene Detail

Summary

• Symbol: Tg(Krt13-cre)139Gaff
• Name: transgene insertion 139, Sarah L Gaffen
• MGI ID: MGI:6379001
• Synonyms: K13^CRE
• Transgene: Tg(Krt13-cre)139Gaff Location: unknown
• Alliance: Tg(Krt13-cre)139Gaff page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Krt13-cre)139Gaff expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Krt13 (MGI:101925)

• Mutation details: The mouse Krt13 promoter derived from BAC RP23-10A2 constitutively drives expression of an NLS (nuclear localization signal)-cre cassette in these transgenic mice. Four PCR+ founders were identified, and tissues were evaluated. Line 139 where Cre expression most closely paralleled the known expression pattern of Krt13 was used for all experiment. (J:281520)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Krt13 (mouse) Summary of all recombinase alleles driven by Krt13. Comparative matrix view of recombinase activities Alliance mouse Krt13 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:281520 Conti HR, et al., IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis. Cell Host Microbe. 2016 Nov 9;20(5):606-617
• All: 3 reference(s)