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Ywhahtm1.2Cya
Targeted Allele Detail
Summary
Symbol: Ywhahtm1.2Cya
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; targeted mutation 1.2, Cyagen Biosciences
MGI ID: MGI:6380693
Synonyms: Ywhahtm1.2Cgen
Gene: Ywhah  Location: Chr5:33176160-33185310 bp, + strand  Genetic Position: Chr5, 17.42 cM, cytoband B1
Alliance: Ywhahtm1.2Cya page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:281426
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. Cre-mediated recombination removed exon 2. (J:281426)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ywhah Mutation:  30 strains or lines available
References
Original:  J:281426 Eisa AA, et al., YWHA (14-3-3) protein isoforms and their interactions with CDC25B phosphatase in mouse oogenesis and oocyte maturation. BMC Dev Biol. 2019 Oct 22;19(1):20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory