Slc18b1^tm1.1Ubc
Targeted Allele Detail

Summary

• Symbol: Slc18b1^tm1.1Ubc
• Name: solute carrier family 18, subfamily B, member 1; targeted mutation 1.1, Uppsala University
• MGI ID: MGI:6383711
• Synonyms: flipped Slc18b1^f
• Gene: Slc18b1 Location: Chr10:23672884-23703866 bp, + strand Genetic Position: Chr10, 11.12 cM
• Alliance: Slc18b1^tm1.1Ubc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282689
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the selection cassette. (J:282689)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc18b1 Mutation: 34 strains or lines available

References

• Original: J:282689 Fredriksson R, et al., The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain. PLoS Genet. 2019 Dec;15(12):e1008455
• All: 1 reference(s)