Percc1^tm1.1Lap
Targeted Allele Detail

Summary

• Symbol: Percc1^tm1.1Lap
• Name: proline and glutamate rich with coiled coil 1; targeted mutation 1.1, Len A Pennacchio
• MGI ID: MGI:6384662
• Synonyms: chr17^deltaICR, Gm38655^tm1.1Lap
• Gene: Percc1 Location: Chr17:25391871-25394445 bp, - strand Genetic Position: Chr17, Syntenic
• Alliance: Percc1^tm1.1Lap page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:279976
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistance cassette replaced 1,512 bp containing the mouse orthologues of the human DNase hypersensitivity signature and the predicted binding sites of FOXA1 and FOXA2. Cre-mediated recombination removed the selection cassette. (J:279976)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Percc1 Mutation: 1 strain or line available

References

• Original: J:279976 Oz-Levi D, et al., Noncoding deletions reveal a gene that is critical for intestinal function. Nature. 2019 Jul;571(7763):107-111
• All: 1 reference(s)