Yeats4^em2Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Yeats4^em2Zfa
• Name: YEATS domain containing 4; endonuclease-mediated mutation 2, Zusen Fan
• MGI ID: MGI:6384943
• Gene: Yeats4 Location: Chr10:117051126-117060412 bp, - strand Genetic Position: Chr10, 65.26 cM, cytoband D2
• Alliance: Yeats4^em2Zfa page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology generated a 1 bp insertion in exon 2 resulting in frameshift mutation and null allele. (J:282740)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yeats4 Mutation: 21 strains or lines available

References

• Original: J:282740 Liu B, et al., Yeats4 drives ILC lineage commitment via activation of Lmo4 transcription. J Exp Med. 2019 Nov 4;216(11):2653-2668
• All: 1 reference(s)