R3hdml^tm1Mita
Targeted Allele Detail

Summary

• Symbol: R3hdml^tm1Mita
• Name: R3H domain containing-like; targeted mutation 1, Minoru Takemoto
• MGI ID: MGI:6385112
• Synonyms: R3hdml^GFP
• Gene: R3hdml Location: Chr2:163334238-163344532 bp, + strand Genetic Position: Chr2, 84.31 cM
• Alliance: R3hdml^tm1Mita page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282737
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Velocigene technology was used to delete a 10-kb region encompassing all coding exons and intervening introns and introduce a GFP reporter gene and loxP-flanked neomycin selection cassette. (J:282737)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any R3hdml Mutation: 18 strains or lines available

References

• Original: J:282737 Sakamoto K, et al., R3hdml regulates satellite cell proliferation and differentiation. EMBO Rep. 2019 Nov 5;20(11):e47957
• All: 1 reference(s)