Ecpas^em1Plch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ecpas^em1Plch
• Name: Ecm29 proteasome adaptor and scaffold; endonuclease-mediated mutation 1, Pei-Lin Cheng
• MGI ID: MGI:6386762
• Synonyms: Ecm29^-
• Gene: Ecpas Location: Chr4:58798911-58912749 bp, - strand Genetic Position: Chr4, 32.35 cM
• Alliance: Ecpas^em1Plch page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a guanine (G) deletion in exon 4 (5'-ACTGCCATGGAAGGGAAA-3' to 5'-ACTGCCATGAAGGGAAA-3'). (J:282974)

Expression

In Mice Carrying this Mutation:

168 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ecpas Mutation: 93 strains or lines available

References

• Original: J:282974 Lee M, et al., Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain. J Cell Biol. 2020 Feb 3;219(2)
• All: 1 reference(s)