Arhgef33^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Arhgef33^em1(IMPC)Tcp
• Name: Rho guanine nucleotide exchange factor 33; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6388389
• Gene: Arhgef33 Location: Chr17:80614836-80707510 bp, + strand Genetic Position: Chr17, 50.63 cM
• Alliance: Arhgef33^em1(IMPC)Tcp page
• IMPC: Arhgef33 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR1466 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GCTTTAGTTTCCTAGTAAGC targeting the 5' side and ATATAGTCCTGGTTAATACT targeting the 3' side of a critical region. This resulted in a 1297-bp deletion Chr17:80346848-80348144 (GRCm38). (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Arhgef33 Mutation: 34 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)