Rorb^tm3.1Df
Targeted Allele Detail

Summary

• Symbol: Rorb^tm3.1Df
• Name: RAR-related orphan receptor beta; targeted mutation 3.1, Douglas Forrest
• MGI ID: MGI:6388502
• Synonyms: Rorb^fl
• Gene: Rorb Location: Chr19:18907969-19088560 bp, - strand Genetic Position: Chr19, 13.28 cM
• Alliance: Rorb^tm3.1Df page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:283416
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The exon encoding the first zinc finger of the DNA-binding domain is flanked by loxP sites. An frt-flanked Neo selection cassette was deleted by FLP recombinase. (J:283416)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rorb Mutation: 39 strains or lines available

References

• Original: J:283416 Byun H, et al., Rorbeta regulates selective axon-target innervation in the mammalian midbrain. Development. 2019 Jul 22;146(14):dev171926
• All: 1 reference(s)