Niban3^tm1Jyw
Targeted Allele Detail

Summary

• Symbol: Niban3^tm1Jyw
• Name: niban apoptosis regulator 3; targeted mutation 1, Ji-Yang Wang
• MGI ID: MGI:6388736
• Synonyms: Bcnp1^-
• Gene: Niban3 Location: Chr8:72050292-72060580 bp, + strand Genetic Position: Chr8, 34.43 cM
• Alliance: Niban3^tm1Jyw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282961
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 6-10 and part of exon 11 were replaced with a neomycin gene. (J:282961)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Niban3 Mutation: 29 strains or lines available

References

• Original: J:282961 Hong R, et al., Distinct roles of BCNP1 in B-cell development and activation. Int Immunol. 2020 Jan 9;32(1):17-26
• All: 1 reference(s)