Tg(Camk2a-MAPT)#Atak
Transgene Detail

Summary

• Symbol: Tg(Camk2a-MAPT)#Atak
• Name: transgene insertion, Akihiko Takashima
• MGI ID: MGI:6389815
• Synonyms: Wtau-Tg
• Transgene: Tg(Camk2a-MAPT)#Atak Location: unknown
• Alliance: Tg(Camk2a-MAPT)#Atak page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Epitope tag, Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-MAPT)#Atak expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MAPT (4137)

  Mapt	(MGI:97180)

• Mutation details: The wild-type human 4 repeat tau containing myc and FLAG tags at the N- and C-terminal ends, respectively, is under the control of the Camk2 promoter which drives expression postnatally in forebrain neurons. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:130237)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:130237 Kimura T, et al., Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau. EMBO J. 2007 Dec 12;26(24):5143-52
• All: 4 reference(s)