Npat^Mpv20
Transgenic Allele Detail

Summary

• Symbol: Npat^Mpv20
• Name: nuclear protein in the AT region; Mpv20 retroviral insertion
• MGI ID: MGI:6390882
• Gene: Npat Location: Chr9:53448347-53485642 bp, + strand Genetic Position: Chr9, 29.12 cM
• Alliance: Npat^Mpv20 page

Transgene origin

• Strain of Origin: CFW

Transgene description

• Transgene Type: Transgenic (Null/knockout)
• Mutation: Insertion
• Mutation details: The Mpv17 mutation was generated by infection of CFW preimplantation mouse embryos with a recombinant retrovirus, MPSVneo, which carries a neo gene and is a replication-defective derivative of the myeloproliferative sarcoma virus, a Moloney murine leukemia virus-related RNA virus. The insertion site. Sequencing data show that the provirus is situated in intron one of the gene in the transcriptional orientation opposite to that of the endogenous coding region. (J:41105)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npat Mutation: 70 strains or lines available

References

• Original: J:41105 Di Fruscio M, et al., Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest. Mol Cell Biol. 1997 Jul;17(7):4080-6
• All: 1 reference(s)