Ccdc166^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccdc166^em1(IMPC)J
• Name: coiled-coil domain containing 166; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6391231
• Gene: Ccdc166 Location: Chr15:75851721-75854134 bp, - strand Genetic Position: Chr15, 35.18 cM
• Alliance: Ccdc166^em1(IMPC)J page
• IMPC: Ccdc166 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAAGGAGTGCTCTAACGAC and CCATTCTGTTGCTCTGGCAA, which resulted in a 2917 bp deletion beginning at Chromosome 15 position 75,979,638 bp and ending after 75,982,554 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001276403 and ENSMUSE00001220008 (exons 1 and 2) and 459 bp of flanking intronic sequence including the splice acceptor, donor and start site and is predicted to generate a null allele. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ccdc166 Mutation: 13 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)