Gm13030^em1Ploen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gm13030^em1Ploen
• Name: predicted gene 13030; endonuclease-mediated mutation 1, Diethard Tautz
• MGI ID: MGI:6392255
• Synonyms: Shj knockout
• Gene: Gm13030 Location: Chr4:138598303-138601275 bp, - strand Genetic Position: Chr4, 70.57 cM
• Alliance: Gm13030^em1Ploen page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 7 bp deletion was created at the beginning of the open reading frame (position 41-47) using an sgRNA with CRISPR/Cas9 technology causing a frameshift and a premature stop codon in exon 2. (J:280745)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gm13030 Mutation: 9 strains or lines available

References

• Original: J:280745 Xie C, et al., A de novo evolved gene in the house mouse regulates female pregnancy cycles. Elife. 2019 Aug 22;8:e44392
• All: 1 reference(s)