Wdr91^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wdr91^em1(IMPC)J
• Name: WD repeat domain 91; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6393542
• Gene: Wdr91 Location: Chr6:34857361-34887766 bp, - strand Genetic Position: Chr6, 15.19 cM
• Alliance: Wdr91^em1(IMPC)J page
• IMPC: Wdr91 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TATCATGATAACGGAGTCCA and CTAGGAAGCTCCCTCAACAG, which resulted in a 329 bp deletion beginning at Chromosome 6 position 34,905,345 bp and ending after 34,905,673 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001222960 (exon 5) and 195 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 198 and early truncation 27 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Wdr91 Mutation: 30 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)