Rnf220^em1Chek
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf220^em1Chek
• Name: ring finger protein 220; endonuclease-mediated mutation 1, Cheol-Hee Kim
• MGI ID: MGI:6393918
• Synonyms: Rnf220^-
• Gene: Rnf220 Location: Chr4:117128660-117354249 bp, - strand Genetic Position: Chr4, 53.44 cM, cytoband D1
• Alliance: Rnf220^em1Chek page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 7 was targeted using an sgRNA and CRISPR/Cas9 technology, resulting in 17 bp deletion (GGGCAGAAGCGGATACG). No peptide expression can be detected from this allele using immunostaining. (J:266544)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf220 Mutation: 323 strains or lines available

References

• Original: J:266544 Kim J, et al., Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains. Development. 2018 Sep 3;145(17):dev165340
• All: 1 reference(s)