Paqr9^em1Jddl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Paqr9^em1Jddl
• Name: progestin and adipoQ receptor family member IX; endonuclease-mediated mutation 1, Jiandie D Lin
• MGI ID: MGI:6394097
• Synonyms: Blnc1^-
• Gene: Paqr9 Location: Chr9:95441710-95450076 bp, + strand Genetic Position: Chr9, Syntenic
• Alliance: Paqr9^em1Jddl page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Transgenic mice carrying the Tg(Rnu6-sgRNA:C730029A08Rik)#Jddl allele, which contains two sgRNAs with targeting sequences flanking this lncRNA locus, were crossed with Cas9-expressing mice (carrying the Gt(ROSA)26Sor^{tm1.1(CAG-cas9*,-EGFP)Fezh} allele) to create this null allele where the entire gene has been deleted. (J:266484)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Paqr9 Mutation: 18 strains or lines available

References

• Original: J:266484 Zhao XY, et al., Long noncoding RNA licensing of obesity-linked hepatic lipogenesis and NAFLD pathogenesis. Nat Commun. 2018 Jul 30;9(1):2986
• All: 1 reference(s)