Fanci^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Fanci^tm1.1Itl
• Name: Fanconi anemia, complementation group I; targeted mutation 1.1, inGenious Targeting Laboratory
• MGI ID: MGI:6394228
• Synonyms: Fanci^loxP
• Gene: Fanci Location: Chr7:79042056-79100013 bp, + strand Genetic Position: Chr7, 45.01 cM
• Alliance: Fanci^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:285384
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exons 2 and 3. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:285384)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fanci Mutation: 200 strains or lines available

References

• Original: J:285384 Dubois EL, et al., A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2. Nucleic Acids Res. 2019 Aug 22;47(14):7532-7547
• All: 1 reference(s)