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Fancitm1.1Itl
Targeted Allele Detail
Summary
Symbol: Fancitm1.1Itl
Name: Fanconi anemia, complementation group I; targeted mutation 1.1, inGenious Targeting Laboratory
MGI ID: MGI:6394228
Synonyms: FanciloxP
Gene: Fanci  Location: Chr7:79042056-79100013 bp, + strand  Genetic Position: Chr7, 45.01 cM
Alliance: Fancitm1.1Itl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:285384
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsLoxP sites were inserted to flank exons 2 and 3. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:285384)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fanci Mutation:  200 strains or lines available
References
Original:  J:285384 Dubois EL, et al., A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2. Nucleic Acids Res. 2019 Aug 22;47(14):7532-7547
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory