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Bcl2l11em1(IMPC)H
Endonuclease-mediated Allele Detail
Summary
Symbol: Bcl2l11em1(IMPC)H
Name: BCL2 like 11; endonuclease-mediated mutation 1, Harwell
MGI ID: MGI:6399901
Gene: Bcl2l11  Location: Chr2:127967958-128004467 bp, + strand  Genetic Position: Chr2, 62.23 cM, cytoband F3-G1
Alliance: Bcl2l11em1(IMPC)H page
IMPC: Bcl2l11 gene page
Mutation
origin
Strain of Origin:  C57BL/6NTac
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 Protein and 2 guide sequences CCTCCCTACAGACAGAACCGCAA, CCCTACAGACAGAACCGCAAGGT, which resulted in a Indel. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Bcl2l11 Mutation:  36 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory