Del(4Sdr16c5-Sdr16c6)1Nyk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(4Sdr16c5-Sdr16c6)1Nyk
• Name: deletion, Chr 4, Natalia Y Kedishvili 1
• MGI ID: MGI:6400351
• Synonyms: Del1Nyk, DKO
• Gene: Del(4Sdr16c5-Sdr16c6)1Nyk Location: unknown Genetic Position: Chr4, Syntenic

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(4Sdr16c5-Sdr16c6)1Nyk involves 2 genes/genome features (Sdr16c5, Sdr16c6) View all
• Mutation details: CRISPR-targeting inserted 298 bp (corresponding to an inverted partial sequence of exon 2) and deleted 56,057 bp spanning exon 5 of Sdr16c5 through exon 5 of Sdr16c6. (J:283063)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(4Sdr16c5-Sdr16c6)1Nyk Mutation: 0 strains or lines available

References

• Original: J:283063 Wu L, et al., Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands. J Biol Chem. 2019 Nov 8;294(45):17060-17074
• All: 2 reference(s)